Penny Moore is a Reader and DST/NRF South African Research Chair of Virus-Host Dynamics at the University of the Witwatersrand and the National Institute for Communicable Diseases in South Africa. Moore holds a joint post as a Research Associate at CAPRISA, University of KwaZulu-Natal. She obtained her MSc at the University of the Witwatersrand, studying gastroenteritis-associated adenoviruses. This was followed by a PhD at the University of London (studying the Hepatitis B virus) in 2003 before returning to South Africa. Her research focuses on HIV broadly neutralizing antibodies, and their interplay with the evolving virus. Recent studies have highlighted the role of viral escape in creating new epitopes and immunotypes, thereby driving the development of neutralization breadth, with implications for HIV vaccine design.