Prof Clare Bryant
Clare Bryant is Professor of Innate Immunity at the University of Cambridge. She graduated in Physiology and Biochemistry, then qualified as a veterinary surgeon, but decided to focus on research rather than clinical work. After completing a PhD at the University of London she worked as a Wellcome Research Fellow with Professor Sir John Vane in London before moving to Cambridge. Her research is focused on understanding how bacterial pathogens are detected by host cell receptors. Her work involves collaborations with mathematicians, physicists and chemists to understand the fundamental molecular mechanisms involved in host-pathogen interactions.
Pereira, M., Tourlomousis, P., Wright, J.A., Monie, T.P., Bryant, C.E. (2016) CARD9 negatively regulates NLRP3-induced IL-1β production upon Salmonella infection of macrophages. Nature Communications 7:12874. doi: 10.1038/ncomms12874
Man, S.M., Hopkins, L.J., Nugent, E., Cox, S., Glück, I., Tourlomousis, P., Wright, J.A., Cicuta, P., Monie, T.P. and Bryant, C.E. (2014) Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macro-molecular complex. Proc Natl Acad Sci 111, 7403-8
Man SM, Ekpenyong A, Tourlomousis P, Achouri S, Cammarota E, Hughes K, Rizzo A, Ng G, Wright JA, Cicuta P, Guck JR, Bryant CE. (2014) Actin polymerization as a key innate immune effector mechanism to control Salmonella infection. Proc Natl Acad Sci. 111:17588-93
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